Optimal Energy Complex combines the best of energy and focus supplements: Caffeine, L-theanine, Theobromine, Theacrine (TeaCrine®), and Dynamine™ (Methylliberine). Caffeine, L-theanine, and Theobromine work together to provide alertness that is balanced by the calming effects of L-theanine. Theacrine (TeaCrine®) is derived from Kucha tea leaves and provides focus and energy. Combining Theacrine with Dynamine™ (Methylliberine) provides exceptional wakefulness without effects on heart rate or blood pressure (1, 2).
WARNING: Optimal Energy Complex is one of the most powerful legal stimulants on the market. DO NOT take more than 1 capsule. DO NOT take if you are sensitive to caffeine or stimulants. We suggest that you take this product with food.
Optimal Energy Complex Benefits
Caffeine + L-Theanine + Theobromine Combination Benefits
- May improve cognitive performance (ref)*
- Promotes the benefits of Caffeine without unwanted effects (ref)*
- Supports focus and attention (ref)*
- Promotes wakefulness and alertness (ref)*
- L-Theanine is General Recognized As Safe (GRAS) by U.S. FDA (ref)*
- A naturally occurring, mild stimulant responsible for the mood-enhancing effects of chocolate (ref)*
Theacrine (TeaCrine®) Benefits
- May enhance energy, focus, and concentration (ref)*
- Non-habit-forming source of energy (ref)*
- GRAS (Generally Recognized as Safe) (ref)*
- Combined with caffeine, supports cognitive function (ref)*
- Combine with caffeine for greater bioavailability (ref)*
Dynamine™ Benefits
- Preliminary clinical trials demonstrate it can be combined with Theacrine (Teacrine®) for exceptional results without stimulatory effects on heart rate or blood pressure elevations (ref)*
- Anecdotal evidence has likened its effects to Theacrine (TeaCrine®) and it may enhance energy, mood, and focus. Clinical, safety, and toxicology studies are taking place currently (ref)*
- GRAS (Generally Recognized as Safe) (ref)*
Optimal Energy Complex Mode of Action
Optimal Energy Complex focuses on methylxanthines (a class of stimulatory compounds), alkaloid compounds which are similar in structure to methylxanthines, and the amino acid found in green tea, L-Theanine. Caffeine, Theobromine, and L-Theanine can all be found naturally occurring together in some teas (3).
Methylxanthines
Methylxanthines include Caffeine and Theobromine and are found together in cocoa, cacao, and chocolate (3).
Caffeine
Caffeine is a stimulant found in coffee, tea, chocolate, guarana, yerba mate, and the kola nut. It is an adenosine receptor antagonist, meaning that it prevents adenosine from being active. Adenosine is one of the neurotransmitters responsible for drowsiness, and caffeine provides wakefulness through this mechanism of blocking adenosine (4).
Caffeine also interacts with the serotonergic system and can cause changes in the acetylcholine and dopamine systems within the body (4).
Theobromine
Theobromine is a mood-enhancing compound naturally present in chocolate. Theobromine is a mild stimulant that interacts with the dopamine pathways in the brain (6). Theobromine stimulates the central nervous system by blocking adenosine receptors (7).
The combination of caffeine and theobromine in chocolate, cocoa, and cacao is linked to the pleasurable effects and appeal of chocolate (8).
Alkaloids similar to methylxanthines
Theacrine and Dynamine™ (Methylliberine) are similar to methylxanthines, but they are structurally different.
Theacrine
Theacrine occurs in Kucha tea leaves and is very similar to a caffeine molecule (1). Theobromine and caffeine in certain plants will convert into Theacrine (9). Theacrine causes signaling changes on the adenosine receptors in the brain, like caffeine, and can also influence the dopaminergic signaling pathways like caffeine. However, unlike caffeine, Theacrine is non-habit forming and does not change the heart rate or blood pressure (1). When combined with caffeine, bioavailability is enhanced (10).
Dynamine™ (Methylliberine)
Dynamine™ (Methylliberine) is an isomer of Theacrine, and it can be found in kucha tea and some species of coffea (9).
Dynamine™ (Methylliberine) provides the effects of Theacrine without any changes in heart rate or blood pressure elevations, and the combination of the two has demonstrated that they are synergistic (2).
L-Theanine is an amino acid which naturally occurs in tea leaves and some forms of mushrooms.
Tea (Camellia sinensis) contains 1-3% of L-theanine. It is used in a supplemental form isolated directly from tea leaves or prepared via chemical synthesis or biosynthesis (11). Green, black, oolong, and white tea all contain L-Theanine in varying amounts (12). Green tea and black tea contain the highest amounts of L-theanine, but the studies are conflicted about which of the two has the most (13).
Combined with caffeine, L-Theanine may improve performance on cognitively demanding tasks through its synergistic effects. L-Theanine may help control blood pressure and may lessen some of the unwanted effects of caffeine (14).
Optimal Energy Complex Dosage
Pure Nootropics’ Optimal Energy Complex provides 100 mg of Caffeine, 200 mg of L-Theanine, 125 mg of Theacrine (TeaCrine®), 125 mg of Dynamine™ (Methylliberine), and 150 mg of Theobromine per 1 capsule. Suggested use for adults is 1 capsule by mouth once daily.
Dynamine™ is a trademark and TeaCrine® is a registered trademark and protected by Patents Pending, Serial No. 61/903,362; under exclusive global distribution by Compound Solutions, Inc.
Optimal Energy Complex Side Effects
This formula contains caffeine which is known to cause side effects and interactions with medications and some herbs. Please use responsibly and avoid if you are sensitive to caffeine. L-Theanine has GRAS status by the U.S. F.D.A. but may possibly reduce blood pressure and interactions could occur with some blood pressure medications, herbs, or other supplements.
If you are taking any medications, herbs, or supplements, please consult your healthcare practitioner before beginning use of a supplement.
For more information, please see our references tab.
The references below are not meant to imply that any of our products treat, cure, or diagnose any disease or human condition. References to clinical studies and pre-clinical studies may use varying dosages and may not represent the dosages or subsequent results of products we sell; however, the references provided are pertinent to the subject supplement itself. References provided are intended for research and informational purposes only and do not represent the entire body of knowledge available on the subject(s) referenced; nor do they represent all possible outcomes associated with the subject(s) referenced including, but not limited to, adverse effects, precautions, or chemical interactions within the human body. The Content provided on this website is not intended to be a replacement for professional medical advice, treatment or diagnosis. Never ignore the advice of a medical professional or delay in attaining professional advice because of information or impressions you gather on this website. Choosing to rely on any information provided by the Content of this website is solely at your own risk. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.
Caffeine + L-Theanine + Theobromine Combination:
May improve cognitive performance* Owen, GN, et al. “The Combined Effects of L-Theanine and Caffeine on Cognitive Performance and Mood.” Nutr Neurosci., vol. 11, no. 4, Aug. 2008, pp. 193–8., doi: doi:10.1179/147683008X301513.
Promotes benefits of caffeine without unwanted effects* Dodd, FL, et al. “A Double-Blind, Placebo-Controlled Study Evaluating the Effects of Caffeine and L-Theanine Both Alone and in Combination on Cerebral Blood Flow, Cognition and Mood.” Pyschopharmacology (Berl), vol. 232, no. 14, July 2015, pp. 2563–76., doi:10.1007/s00213-015-3895-0.
Supports focus and attention* Kahathuduwa, CN, et al. “l-Theanine and Caffeine Improve Target-Specific Attention to Visual Stimuli by Decreasing Mind Wandering: a Human Functional Magnetic Resonance Imaging Study.” Nutr Res., vol. 49, Jan. 2018, pp. 67–78., doi:10.1016/j.nutres.2017.11.002.
Promotes wakefulness and alertness* Giesbrecht, T, et al. “The Combination of L-Theanine and Caffeine Improves Cognitive Performance and Increases Subjective Alertness.” Nut, vol. 13, no. 6, Dec. 2010, pp. 283–90., doi:10.1179/147683010X12611460764840.
General Recognized as Safe (GRAS) by U.S. FDA “GRAS Notices.” U.S. Food & Drug Administration, www.accessdata.fda.gov/scripts/fdcc/index.cfm?set=GrASNotices&sort=Date_of_closure&order=ASC&showAll=true&type=basic&search=theanine.
Theobromine: A naturally occurring, mild stimulant responsible for the mood enhancing effects of chocolate* Baggott, Matthew J et al. “Psychopharmacology of theobromine in healthy volunteers.” Psychopharmacology vol. 228,1 (2013): 109-18. doi:10.1007/s00213-013-3021-0.
Theacrine (TeaCrine®): May enhance energy, focus, and concentration* Ziegenfuss, TN, et al. “A Two-Part Approach to Examine the Effects of Theacrine (TeaCrine®) Supplementation on Oxygen Consumption, Hemodynamic Responses, and Subjective Measures of Cognitive and Psychometric Parameters.” J Diet Suppl, vol. 14, no. 1, 2 Jan. 2017, pp. 9–24., doi:10.1080/19390211.2016.1178678.
Non-habit-forming source of energy * Taylor, L, et al. “Safety of TeaCrine®, a Non-Habituating, Naturally-Occurring Purine Alkaloid over Eight Weeks of Continuous Use.” J Int Soc Sports Nutr, vol. 13, no. 2, 13 Jan. 2016, doi:10.1186/s12970-016-0113-3.
GRAS (Generally Recognized as Safe by US FDA)* “Teacrine.” Compound Solutions, www.compoundsolutions.com/science.html.
Combined with caffeine, supports cognitive function* Bello, ML, et al. “The Effects of TeaCrine® and Caffeine on Endurance and Cognitive Performance during a Simulated Match in High-Level Soccer Players.” J Int Soc Sports Nutr, vol. 16, no. 1, 18 Apr. 2019. Compound Solutions, doi:10.1186/s12970-019-0287-6.
Combine with caffeine for greater bioavailability* He, Hui et al. “Assessment of the Drug-Drug Interaction Potential Between Theacrine and Caffeine in Humans.” Journal of caffeine research vol. 7,3 (2017): 95-102. doi:10.1089/jcr.2017.0006 Dynamine™:
Preliminary clinical trials demonstrate it can be combined with Theacrine (Teacrine®) Capsules for exceptional results without stimulatory effects on heart rate or blood pressure elevations* “Proceedings of the Fifteenth International Society of Sports Nutrition (ISSN) Conference and Expo: Clearwater Beach, FL, USA. 7-9 June 2018.” Journal of the International Society of Sports Nutrition vol. 15,Suppl 1 1–37. 6 Nov. 2018, doi:10.1186/s12970-018-0256-5
Anecdotal evidence has likened its effects to Theacrine (TeaCrine®) and it may enhance energy, mood, and focus.
Clinical, safety, and toxicology studies are taking place currently* “Dynamine™.” Compound Solutions, www.compoundsolutions.com/dynamine.html.
1. “Theacrine.” Examine.com, published Nov 20, 2013. Last updated Jun 14, 2018. https://examine.com/supplements/theacrine/.
2. “Proceedings of the Fifteenth International Society of Sports Nutrition (ISSN) Conference and Expo: Clearwater Beach, FL, USA. 7-9 June 2018.” Journal of the International Society of Sports Nutrition vol. 15,Suppl 1 1–37. 6 Nov. 2018, doi:10.1186/s12970-018-0256-5
3. IARC Working Group on the Evaluation of Carcinogenic Risk to Humans. Coffee, Tea, Mate, Methylxanthines and Methylglyoxal. Lyon (FR): International Agency for Research… 1991. (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 51.) Theobromine. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507032/.
4. “Caffeine”. Examine.com, published on Jul 26 2014, Last updated Mar 29, 2019. https://examine.com/supplements/caffeine/.
5. Evans J, Battisti AS. Caffeine. [Updated 2019 Jan 16]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-. Available from: https://www.ncbi.nlm.nih.go/books/NBK519490/.
6. “Where do cravings come from?” Examine.com, published Apr 17, 2017, Last updated Apr 18, 2017. https://examine.com/nutrition/where-do-cravings-come-from/.
7. Franco, R, et al. “Health Benefits of Methylxanthines in Cacao and Chocolate.” Nutrients., vol. 5, no. 10, 18 Oct. 2018, pp. 4159–73., doi:10.3390/nu5104159.
8. Baggott, Matthew J., et al. “Psychopharmacology of Theobromine in Healthy Volunteers.” Psychopharmacology, 31 Jan. 2013, doi:10.1007/s00213-013-3021-0.
9. Petermann, JB, and TW Baumann. “Metabolic Relations between Methylxanthines and Methyluric Acids in Coffea L.” Plant Physiol., vol. 73, no. 4, Dec. 1983, pp. 961–4., www.ncbi.nlm.nih.gov/pubmed/?term=methylliberine.
10. He, Hui et al. “Assessment of the Drug-Drug Interaction Potential Between Theacrine and Caffeine in Humans.” Journal of caffeine research vol. 7,3 (2017): 95-102. doi:10.1089/jcr.2017.0006
11. “Theanine.” Food, Herbs & Supplements, Professional. Natural Medicines, Therapeutic Research, naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=1053.
12. Boros, Klára et al. “Theanine and Caffeine Content of Infusions Prepared from Commercial Tea Samples” Pharmacognosy magazine vol. 12,45 (2016): 75-9.
13. Keenan, Emma and D. A. Finnie, Mike and S. Jones, Paul and J. Rogers, Peter and Priestley, Caroline. How much theanine in a cup of tea? Effects of tea type and method of preparation, Food Chemistry - FOOD CHEM, March 2011, Vol. 125, pp. 588-594, doi:10.1016/j.foodchem.2010.08.071.
14. Owen, GN, et al. “The Combined Effects of L-Theanine and Caffeine on Cognitive Performance and Mood.” Nutr Neurosci., vol. 11, no. 4, Aug. 2008, pp. 193–8., doi: doi.org/10.1179/147683008X301513.
15. “Caffeine.” Food, Herbs & Supplements, Professional. Natural Medicines, Therapeutic Research, https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=979#toxicology.
16. "3,7-Dimethylxanthine (Theobromine)". Toxnet, US National Library of Medicine. 1 December 2017. Retrieved 13 November 2018.
17. “Theobromine.” Wikipedia, en.wikipedia.org/wiki/Theobromine#cite_ref-33.
18. Taylor, Lem et al. “Safety of TeaCrine®, a non-habituating, naturally-occurring purine alkaloid over eight weeks of continuous use.” Journal of the International Society of Sports Nutrition vol. 13 2. 13 Jan. 2016, doi:10.1186/s12970-016-0113-3. Caffeine Anhydrous of Analysis 03/20 L-Theanine Certificate of Analysis 07/19
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