Agmatine is a decarboxylated derivative of the amino acid L-arginine (1).
Agmatine Sulfate Mode of Action
Agmatine is an amine molecule that is involved in signaling in the human body. It is a bacterial byproduct and can be found in fermented foods such as wine, beer, sake, fish, meat products, and coffee (1).
Agmatine is endogenously produced and is found in the spinal cord and brain. Agmatine interacts with cell-specific receptors and interacts with actions within the central nervous system. However, its role in brain function has not yet been determined because researchers are still studying its biosynthesis and degradation (4).
Agmatine Sulfate Dosage
Pure Nootropics’ Agmatine Sulfate provides 500 mg per 1 capsule.
For further information, please see our References Tab above.
The references below are not meant to imply that any of our products treat, cure, or diagnose any disease or human condition. References to clinical studies and pre-clinical studies may use varying dosages and may not represent the dosages or subsequent results of products we sell; however, the references provided are pertinent to the subject supplement itself. References provided are intended for research and informational purposes only and do not represent the entire body of knowledge available on the subject(s) referenced; nor do they represent all possible outcomes associated with the subject(s) referenced including, but not limited to, adverse effects, precautions, or chemical interactions within the human body. The Content provided on this website is not intended to be a replacement for professional medical advice, treatment or diagnosis. Never ignore the advice of a medical professional or delay in attaining professional advice because of information or impressions you gather on this website. Choosing to rely on any information provided by the Content of this website is solely at your own risk. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.
2. “Arginine.” Examine.com, published Oct 16, 2014. Last updated Jun 14, 2018. https://examine.com/supplements/arginine/.
4. Reis, DJ, and S Regunathan. “Agmatine: a Novel Neurotransmitter?” Adv. Pharmacol, vol. 42, 1998, pp. 645–9., www.ncbi.nlm.nih.gov/pubmed/9327985.
5. Arndt, Mary Ann et al. “The arginine metabolite agmatine protects mitochondrial function and confers resistance to cellular apoptosis.” American journal of physiology. Cell physiology vol. 296,6 (2009): C1411-9. doi:10.1152/ajpcell.00529.2008
6. Gilad, GM, and VH Gilad. “Evidence for Oral Agmatine Sulfate Safety–a 95-Day High Dosage Pilot Study with Rats.” Food Chem Toxicol., vol. 62, Dec. 2013, pp. 758–62., doi:10.1016/j.fct.2013.10.005.
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