N-Acetyl-L-Tyrosine is an acetylated form of L-Tyrosine, the amino acid which synthesizes essential neurotransmitters (1)(2).
N-Acetyl-L-Tyrosine Benefits
- Increased solubility and better bioavailability than L-Tyrosine alone (ref)*
- Supports cognitive health (ref)*
- Promotes cognitive performance and flexibility during mental performance (ref)*
- Promotes a healthy response to acute stress (ref)*
N-Acetyl-L-Tyrosine Mode of Action
Due to the poor solubility of L-Tyrosine, N-acetyl-L-tyrosine is an L-tyrosine molecule to which an acetyl molecule has been added to enhance the solubility and bioavailability of L-tyrosine (1).
L-Tyrosine is an amino acid involved in producing neurotransmitters such as dopamine and adrenaline (2).
L-Tyrosine can help stress response mechanisms during acute and uncontrollable stress. Unlike adaptogens which help alleviate symptoms of chronic stress, L-Tyrosine's benefits regarding stress can be seen during acute and sudden stress (2).
L-Tyrosine may support a positive mood under stressful situations which deplete norepinephrine and dopamine from the brain (3).
L-Tyrosine can be food in chicken, turkey, milk, fish, yogurt, cheese, almonds, peanuts, soy products, pumpkin seeds, sesame seeds, avocados, and bananas (4).
N-Acetyl-L-Tyrosine Capsules or Powder Dosage
Pure Nootropics’ N-Acetyl-L-Tyrosine (NALT) capsules provide 350 mg per 1 capsule. Suggested use for adults is 1 capsule by mouth daily (or 350 mg weighed on a milligram scale daily), or as directed by your healthcare practitioner.
If you are taking any medications, please consult your healthcare practitioner before beginning supplementation with L-Tyrosine.
For further information, please see our References Tab above.
The references below are not meant to imply that any of our products treat, cure, or diagnose any disease or human condition. References to clinical studies and pre-clinical studies may use varying dosages and may not represent the dosages or subsequent results of products we sell; however, the references provided are pertinent to the subject supplement itself. References provided are intended for research and informational purposes only and do not represent the entire body of knowledge available on the subject(s) referenced; nor do they represent all possible outcomes associated with the subject(s) referenced including, but not limited to, adverse effects, precautions, or chemical interactions within the human body. The Content provided on this website is not intended to be a replacement for professional medical advice, treatment or diagnosis. Never ignore the advice of a medical professional or delay in attaining professional advice because of information or impressions you gather on this website. Choosing to rely on any information provided by the Content of this website is solely at your own risk. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.
• Increased solubility and better bioavailability than L-Tyrosine alone*
“N-Acetyl-L-Tyrosine (Compound).” PubChem Open Chemistry Database, pubchem.ncbi.nlm.nih.gov/compound/N-Acetyl-L-tyrosine#section=Drug-Indication.
• Supports cognitive health*
Colzato, Lorenza S et al. “Working memory reloaded: tyrosine repletes updating in the N-back task.” Frontiers in behavioral neuroscience vol. 7 200. 16 Dec. 2013, doi:10.3389/fnbeh.2013.00200
• Promotes cognitive flexibility during mental performance*
Steenbergen L, Sellaro R, Hommel B, Colzato LS. Tyrosine promotes cognitive flexibility: evidence from proactive vs. reactive control during task switching performance. Neuropsychologia. 2015 Mar;69:50-5. doi: 10.1016/j.neuropsychologia.2015.01.022. Epub 2015 Jan 16. PMID: 25598314.
• Promotes a healthy response to acute stress*
Banderet, LE, and HR Lieberman. “Treatment with Tyrosine, a Neurotransmitter Precursor, Reduces Environmental Stress in Humans.” Brain Res Bull., vol. 22, no. 4, Apr. 1989, pp. 759–62., www.ncbi.nlm.nih.gov/pubmed/2736402.
1. “N-Acetyl-L-Tyrosine (Compound).” PubChem Open Chemistry Database, pubchem.ncbi.nlm.nih.gov/compound/N-Acetyl-L-tyrosine#section=Drug-Indication.
2. “L-Tyrosine”. Examine.com, published Jun 22, 2013. Last updated Jan 25, 2019. https://examine.com/supplements/l-tyrosine/.
3. Banderet, LE, and HR Lieberman. “Treatment with Tyrosine, a Neurotransmitter Precursor, Reduces Environmental Stress in Humans.” Brain Res Bull., vol. 22, no. 4, Apr. 1989, pp. 759–62., www.ncbi.nlm.nih.gov/pubmed/2736402.
4. “L-Tyrosine.” Wikipedia, en.wikipedia.org/wiki/Tyrosine
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