N-Acetyl-Cysteine (NAC) supports cellular health and is the precursor for glutathione (1).
N-Acetyl-L-Cysteine Benefits
- Free Radical Protection (ref)*
- Maintains cellular health*
N-Acetyl-L-Cysteine Mode of Action
N-acetylcysteine is an acetylated form of L-Cysteine. By supplementing with NAC, there is more L-cysteine available to replenish Glutathione (2).
Glutathione's primary function is to provide free radical defense and modulate oxidation-reduction reaction signal transduction within the cells (3).
NAC increases intracellular Glutathione and also provides its own direct free radical protection by defending against ROS (reactive oxygen species), helping to maintain proper cellular health against oxidative stressors (3).
N-Acetyl-L-Cysteine Dosage
Pure Nootropics’ NAC provides 500 mg per 1 capsule. Suggested use for adults is 1 capsule by mouth daily (or 500 mg powder weighed on a milligram scale once daily), or as directed by your healthcare practitioner.
If you are taking any medications, please consult your healthcare practitioner before beginning supplementation.
For further information, please see our References Tab above.
The references below are not meant to imply that any of our products treat, cure, or diagnose any disease or human condition. References to clinical studies and pre-clinical studies may use varying dosages and may not represent the dosages or subsequent results of products we sell; however, the references provided are pertinent to the subject supplement itself. References provided are intended for research and informational purposes only and do not represent the entire body of knowledge available on the subject(s) referenced; nor do they represent all possible outcomes associated with the subject(s) referenced including, but not limited to, adverse effects, precautions, or chemical interactions within the human body. The Content provided on this website is not intended to be a replacement for professional medical advice, treatment or diagnosis. Never ignore the advice of a medical professional or delay in attaining professional advice because of information or impressions you gather on this website. Choosing to rely on any information provided by the Content of this website is solely at your own risk. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.
• Free Radical Protection*
Santus, Pierachille et al. “Oxidative stress and respiratory system: pharmacological and clinical reappraisal of N-acetylcysteine.” COPD vol. 11,6 (2014): 705-17. doi:10.3109/15412555.2014.898040.
1. Millea, Paul J. “N-Acetylcysteine: Multiple Clinical Applications.” Am Fam Physician, vol. 80, no. 3, 1 Aug. 2009, pp. 265–269., www.aafp.org/afp/2009/0801/p265.html.
2. “N-Acetylcysteine”. Examine.com, published Sep 11, 2013. Last updated Jun 14, 2018. https://examine.com/supplements/n-acetylcysteine/.
3. Bavarsad Shahripour, Reza et al. “N-acetylcysteine (NAC) in neurological disorders: mechanisms of action and therapeutic opportunities.” Brain and behavior vol. 4,2 (2014): 108-22. doi:10.1002/brb3.208.
4. Santus, Pierachille et al. “Oxidative stress and respiratory system: pharmacological and clinical reappraisal of N-acetylcysteine.” COPD vol. 11,6 (2014): 705-17. doi:10.3109/15412555.2014.898040.
5. “N-Acetyl Cysteine”. Food, Herbs & Supplements, Professional. Natural Medicines, Therapeutic Research, https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=1018#adverseEvents.
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